Monday, January 25, 2010

Aditya Dev - world's smallest body builder


Primordial Dwarfism

Osteodysplastic Primordial Dwarfism

Meier-Gorlin Syndrome

There are as yet no effective treatments for primordial dwarfism. It is known that PD is caused by inheriting a mutant gene from each parent. The lack of normal growth in the disorder is not due to a deficiency of growth hormone, as in hypopituitary dwarfism. Administering growth hormone, therefore, has little or no effect on the growth of the individual with primordial dwarfism. In January 2008, it was published that mutations in the pericentrin gene (PCNT) were found to cause primordial dwarfism. Pericentrin has a role in cell division, proper chromosome segregation, and cytokinesis suggesting these processes are important. -Wikipedia




Lucia Zarate - first person diagnosed with MOPD
b. 1864
wt. 4.7 lbs
She first worked as part of an act billed as the "Fairy Sisters", later partnering with Francis Joseph Flynn (billed under the stage name "General Mite") to exhibit internationally. In 1889 she was billed in The Washington Post as the "marvelous Mexican midget" and described as "a tiny but all powerful magnet to draw the public." When her circus train became stranded in snow in the Sierra Nevada mountains in 1890, Zarate died of hypothermia in 1890.

No comments: